Drug |
Type of reported reaction |
Percentage and severity of eosinophilia |
Chloroquine and Hydroxychloroquine |
Pulmonary and Immunologic |
Drug reaction with eosinophilia and systemic symptomsDRESS syndromeSevere based on case reports, frequency not defined |
Macrolides: Azithromycin |
Pulmonary and dermal |
Eosinophilia <1%, (severity unclear) |
Vancomycin |
Dermal and renal |
Eosinophilia 1-10% (moderate to severe, reversible) |
Teicoplanin |
Dermal and renal |
Eosinophilia <1%, (severity unclear) |
Cephalosporins |
Cardiac, pulmonary and dermal |
Usually mild and self-limiting |
Ceftriaxone |
Cardiac, pulmonary and dermal |
Eosinophilia 6%, (mild) |
Cefuroxime |
Pulmonary and dermal |
Eosinophilia 1-7%, (mild) |
Cefepime |
Pulmonary and dermal |
Eosinophilia 2%, (mild) |
Piperacillin tazobactam |
Renal and dermal |
Eosinophilia frequency not defined, (mild). |
Sulphonamides |
Pulmonary and cardiac |
Not usually reported, (could be severe) |
Trimethoprim-sulfamethoxazole(Co-trimoxazole). |
Pulmonary and cardiac |
Eosinophilia frequency not defined, (mild to moderate) |