Table 2.

Predictive factors of viral clearance by Poisson regression analysis.

	Crude IRR (95 % CI)		p-value		Adjusted IRR (95 % CI)		p-value
Gender
Male vs Female	1.01 (0.82–1.26)	0.904		1.03 (0.82–1.29)		0.798
Age
For 10 years older	0.96 (0.90–1.02)	0.217		1.03 (0.95–1.12)		0.419
Underlying comorbidities
For each more	0.90 (0.84−0.97)	0.005		0.88 (0.80−0.96)		0.004
Inflammatory index at hospital admission
Lymphocytes count < 1.0 × 109/L	0.69 (0.54−0.87)	0.002		0.75 (0.58−0.98)		0.032
D-dimer > 103 ng/mL	1.16 (0.89–1.51)	0.271
Serum Ferritin > 500 ng/mL	1.07 (0.82–1.39)	0.631
Severity of respiratory diseasea
PaO2/FiO2 ≤ 200 versus > 200 mmHg	0.61 (0.47−0.79)	<0.001		0.42 (0.27−0.66)		<0.001
Time from symptoms onset to admission
for 1 day more	0.98 (0.97−0.99)	<0.001		1.00 (0.99–1.00)		0.378
Antiviral therapya
Yes versus no	2.81 (2.23–3.53)	<0.001		1.16 (0.77–1.74)		0.490
Corticosteroidsa
Yes versus no	1.57 (1.25–1.95)	<0.001		1.12 (0.85–1.46)		0.419
Cytokines inhibitors
Yes versus no	1.04 (0.81–1.33)	0.783		0.95 (0.73–1.23)		0.677

Abbreviations: IRR, incidence rate ratio; CI, confidence interval.

^aTime updated variable.