Table 2.
Demographics and clinical lab results for study participants included in the interim analysis.
| HWC | OB | FDR adj. P value | |
|---|---|---|---|
| Participants | 27 | 27 | |
| Sex (F/M/NA) | 15/12/0 (55/45/0%) | 15/12/0 (55/45/0%) | |
| Race: | |||
| Black | 13 (48.1%) | 12 (44.4%) | |
| White | 12 (44.4%) | 11 (40.1%) | |
| Black/White | 0 | 2 (7.4%) | |
| Other | 2 (7.4%) | 2 (7.4%) | |
| Average %95th BMI* | 75.6 ± 5.1 | 137.8 ± 48.7 | 0.05−11 |
| Average Age at Entry | 15.0 ± 1.7 | 12.6 ± 2.4 | 0.06 |
| Clinical Labs: | |||
| Triglycerides (mg/dl) (mg(mg/dl( | 84.7 ± 35.6 | 113.7 ± 75.2 | 0.14 |
| HDL (mg/dl) | 54.1 ± 14.1 | 45.6 ± 11.1 | 0.02 |
| LDL (mg/dl) | 84.9 ± 30.5 | 100.1 ± 25.3 | 0.06 |
| Glucose (mg/dl) | 84.6 ± 9.9 | 88.9 ± 9.1 | 0.12 |
| HOMA-IR | 2.4 ± 2.8 | 4.0 ± 3.1 | 0.01 |
| HbA1c (IU/dl) | 5.2 ± 0.3 | 5.4 ± 0.4 | 0.01 |
| Cholesterol (mg/dl) | 155.9 ± 38.7 | 163.9 ± 29.0 | 0.41 |
Numbers respresent actual number of participants or mean result ± standard deviation.
*:
percent of the BMI value at the 95th percentile.
NA, Not Available; HDL, high density lipoprotein; LDL, low density lipoprotein; HbA1c, percent acylated (glycated) hemoglobin; HOMA-IR, homeostatic model of insulin resistance; Mg/dl, milligrams/deciliter of blood; IU, International Units