TABLE 2.
Haemodynamics in the two groups during the period of maintenance#
| Events | Dexmedetomidine | Propofol | p-value |
| Subjects n | 25 | 25 | |
| Blood pressure mmHg | |||
| Lowest MAP | 79.2±9.9 | 72.5±12.9 | 0.04 |
| ΔMAP¶ | −16.7±13.8 | −21.9±13.6 | 0.1 |
| MAP <65 mmHg | 1 (4.0) | 5 (20.0) | 0.2 |
| Lowest SBP | 106.7±13.8 | 98.2±13.4 | 0.049 |
| ΔSBP¶ | −24.9±15.7 | −36.0±23.2 | 0.1 |
| SBP <90 mmHg | 3 (12.0) | 7 (28.0) | 0.3 |
| Heart rate beats·min−1 | |||
| Lowest heart rate | 60.9±10.2 | 71.4±11.8 | 0.006 |
| Δheart rate¶ | −13.6±9.3 | −3.3±9.1 | <0.001 |
| Heart rate <60 beats·min−1 | 12 (48.0) | 4 (16.0) | 0.03 |
| Oxygenation % | |||
| Lowest SpO2 | 90.9±5.2 | 87.9±6.3 | 0.1 |
| ΔSpO2¶ | −8.3±5.3 | −10.9±6.2 | 0.1 |
| SpO2 <90% | 8 (32.0) | 14 (56.0) | 0.2 |
| Mean BIS | 84.1±8.3 | 73.6±5.7 | <0.001 |
Data are presented as mean±sd or n (%), unless otherwise stated. MAP: mean arterial pressure; SBP: systolic blood pressure; SpO2: oxyhaemoglobin saturation; BIS: bispectral index. #: duration from insertion of bronchoscope to withdrawal; ¶: Δ is defined as the difference between the lowest level of vital signs during the period of bronchoscopic procedures and that before induction.