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PARP-1 inhibition attenuates the pro-inflammatory gene expression changes induced by S100B. A. Effects of the PARP inhibitor veliparib (5 μM) on gene expression changes induced by 200 ng/ml S100B. B. Effects of PARP-1−/− genotype on gene expression changes induced by 200 ng/ml S100B. n = 3, *P < 0.05, **P < 0.01.
