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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Toxicol In Vitro. 2021 Jan 23;72:105102. doi: 10.1016/j.tiv.2021.105102

Table 7.

Butyrylcholinesterase inhibition by various organophosphates in rat serum.

Serum Butyrylcholinesterase
PND 1 PND 12 PND 70
Oxon IC50 nM (95%CI) IC50 nM (95%CI) IC50 nM (95%CI)
Azinphos-methyl-oxon 1051 (931,1382) 1259 (1181,1337) 1433 (1176,1691)
Methyl paraoxon 389 (386,392) 381 (357,406) 394 (337,452)
Dicapthon-oxon 58 (55,62) 57 (53,61) 185* (179,192)
Methyl coumaphos-oxon 1223 (1137,1308) 1212 (1191,1234) 1469 (1116,1821)
Paraoxon 47 (46,48) 52 (50,54) 76* (58,94)
Chlorpyrifos-oxon 6 (5,7) 7 (6,7) 39* (30,49)
Ethyl cyanophos-oxon 208 (167,249) 224 (180,268) 339* (282,396)
Ethyl ronnel-oxon 2 (1,3) 7 (3,8) 35* (23,48)
Diazoxon 8 (7,9) 10 (9,11) 31* (30,33)
Naftalophos 5 (4,6) 7 (6,7) 30* (37,43)
Nitropyrifos-oxon 15 (14,16) 14 (13,15) 64* (56,73)
Phoxim-oxon 2 (1,3) 31* (26,36) 60* (57,64)
g

IC50s are expressed as means with 95% confidence intervals of three independent replications for each age group. Means for each compound followed by an * are significantly different (p < 0.05) among ages within a tissue.