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. Author manuscript; available in PMC: 2021 Mar 3.
Published in final edited form as: Small. 2021 Jan 25;17(7):e2004975. doi: 10.1002/smll.202004975

Figure 11.

Figure 11.

Variations in pain behavior in rats. Notes: Mechanical (A) and heat (B) hyperalgesia behaviors measured every week after endometriotic or sham surgery. C and D) Hyperalgesia behavior observed at 2, 4, 8, 12, 18, and 24 h after drug administration in normal rats. E and F) Behavior tested after drug administration in endometriotic rats. Data are expressed as the mean (SEM; A and B, n=15; C–F, n=5). *P<0.05; **P<0.01; ***P<0.001. Abbreviations: CSOSA, chitosan oligosaccharide-g-stearic acid; Ctrl, control group; Em, endometriotic group; HSL, heat source latency; MPT, mechanical pain threshold; NLC, nanostructured lipid carrier; SEM, standard error of mean. Reproduced with permission.[44] Copyright 2017, Dovepress.