Table 1.

Summary of reported nanomedicines for endometriosis imaging and treatment.

Application	Nanomaterial	Cargo	References
MRI	Iron oxide nanoparticles	N/A	Lee et al., 2012[49] Zhang et al., 2014[60]
Fluorescence imaging	PEG-PCL polymeric nanoparticles	NIR dye (SiNc)	Moses et al., 2020[11]
Photothermal therapy	Hollow gold nanospheres	N/A	Guo et al., 2017[43]
	PEG-PCL polymeric nanoparticles	NIR dye (SiNc)	Moses et al., 2020[11]
Gene Therapy	Lipid-chitosan micelles-DNA polyplex	Plasmid DNA	Zhao et al., 2012[45]
	PAMAM dendrimer-DNA polyplex	Plasmid DNA	Wang et al., 2014[104]
	PEI–PEG–RGD-miRNA polyplex	miRNA	Liang et al., 2017[98]
	PEI-chitosan oligosaccharide–siRNA polyplex	siRNA	Zhao et al., 2016[61]
Combinatorial therapy	PLGA polymeric nanoparticles	Curcumin & letrozole	Jana et al., 2014[100]
		Epigallocatechin gallate & doxycycline	Singh et al., 2015[101]
Pain treatment	Lipid grafted chitosan micelles-coated nanostructured lipid carriers	P2X3 receptor antagonist (A317491)	Yuan et al., 2017[44]
Antioxidant therapy	Cerium oxide nanoparticles	N/A	Chaudhury et al., 2012[99]
Immunotherapy	Mesoporous silica nanoparticles	Immunomodulatory drug	Antsiferova et al., 2013[186]
	PLGA polymeric nanoparticles	Antibody	Liu et al., 2017[103]
Natural product-based therapy	Silicate nanocomposite (VB8)	Copaiba oleoresin	de Almeida Borges et al., 2016[198] Henriques da Silva et al., 2015[200]
	PLGA polymeric nanoparticles		de Almeida Borges et al., 2018[199]
Local therapy	PEG&PCL nanofibers	Curcumin	Boroumand et al., 2019[102]
Biodistribution in patients	Lipid core nanoparticles	N/A	Pogdaec et al., 2019[70]