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. Author manuscript; available in PMC: 2021 Mar 3.
Published in final edited form as: Arthritis Rheumatol. 2018 Mar 2;70(4):578–584. doi: 10.1002/art.40384

Table 4. Initial chikungunya symptoms and baseline co-morbidities by gender.

Significant p-values after Bonferroni-adjustment are in bold.

Characteristic n (%) Female (n=388) Male (n=95) p-value
Initial Symptoms
Muscle pain 377 (97%) 93 (98%) 0.99
Weakness 353 (91%) 73 (77%) <0.0001
Joint pain and/or inflammation 383 (99%) 92 (97%) 0.19
Rash/itch 339 (87%) 69 (73%) 0.0004
Fever 304 (80%) 71 (76%) 0.49
Headache 291 (75%) 62 (65%) 0.06
Lymphadenopathy 287 (74%) 55 (58%) 0.002
Cool extremities 216 (56%) 40 (42%) 0.018
Nausea or vomiting 157 (41%) 21 (22%) 0.0004
Bruising 69 (18%) 7 (7%) 0.012
Hemorrhage 8 (2%) 3 (3%) 0.46
Nose bleed 3 (1%) 2 (2%) 0.25
Oral bleeding 4 (1%) 2 (2%) 0.34
Initial Rheumatic Symptoms
Wrist pain 347 (91%) 78 (85%) 0.10
Ankle pain 331 (86%) 80 (87%) 0.89
Finger pain 325 (85%) 77 (83%) 0.62
Elbow pain 329 (86%) 65 (71%) 0.0005
Toe pain 312 (82%) 74 (80%) 0.78
Knee pain 306 (80%) 76 (82%) 0.72
Hip pain 286 (75%) 55 (59%) 0.0022
Prior Comorbidities
Arthritis 9 (2%) 8 (9%) 0.009
Chronic foot pain 8 (2%) 6 (6%) 0.04
Gout 7 (2%) 5 (5%) 0.07
Osteoarthritis 10 (3%) 3 (3%) 0.73
Heart disease 10 (3%) 3 (3%) 0.73
Kidney disease 10 (3%) 2 (2%) 0.99
Lung disease 17 (4%) 2 (2%) 0.39
Diabetes 31 (8%) 3 (3%) 0.10
HTN 47 (12%) 10 (11%) 0.66
Depression 15 (4%) 5 (5%) 0.58

P<0.00167 required