TABLE 3.
Impact of miR-148a expression on % DNA global methylation (% 5-mC DNA) of Pb-exposed workers from automotive battery factories. Adjusted for age, BMI, alcohol consumption, smoking, and blood lead levels (BLL).
| Variables | % 5-mC DNA | ||
| βc | p | 95% CI | |
| Age | −0.014 | 0.23 | −0.30; 0.0090 |
| BMIa | 0.020 | 0.55 | −0.48; 0.89 |
| Alcoholb | |||
| No | −0.12 | 0.65 | −0.66; 0.42 |
| Yes | – | – | |
| Smokingb | |||
| No | −0.13 | 0.72 | −0.88; 0.61 |
| Yes | – | – | |
| BLLa | −0.023 | 0.44 | −0.83; 0.037 |
| miR-148a | −3.7 | 0.071 | −7.8; 0.32 |
asqrt-transformed; byes was taken as reference; Cunstandardized beta (β) coefficients for covariates in the model. Math model: % 5-mC DNA = α + β1 × age + β2 × BMI + β3 × alcohol + β4 × smoking + β5 × BLL + β6 × miR-148a.