Table 3. Comparison of Clinical and Laboratory Parameters in Patients with SFTS Within 48 Hours Before and After Steroid Treatment.
| Within 48 h before treatment | Within 48 h after treatment | (n = 41) | |||||
|---|---|---|---|---|---|---|---|
| Variables | n | Median | (IQR) | n | Median | (IQR) | P Valuea |
| GCS score | 39 | 14.0 | (11.0–15.0) | 39 | 12.0 | (8.0–15.0) | .002 |
| BT (°C) | 30 | 38.3 | (37.6–38.7) | 39 | 37.0 | (36.4–37.7) | < .001 |
| WBC (/μL) | 40 | 1700.0 | (1140.0–2837.5) | 41 | 3200.0 | (2500.0–5150.0) | < .001 |
| Neutrophil (%) | 40 | 59.9 | (47.1–69.7) | 38 | 59.6 | (43.5–69.3) | .934 |
| ANC | 40 | 1047.9 | (615.1–1574.7) | 38 | 2010.3 | (1110.9–3236.1) | < .001 |
| Lymphocyte (%) | 40 | 27.3 | (17.5–35.4) | 38 | 28.3 | (17.0–37.8) | .695 |
| ALC | 40 | 409.1 | (291.7–826.2) | 38 | 794.8 | (520.2–1467.2) | .003 |
| Hgb (g/dL) | 40 | 12.7 | (11.9–14.5) | 41 | 12.0 | (10.2–13.3) | < .001 |
| Hct (%) | 40 | 36.5 | (34.3–40.4) | 41 | 34.4 | (30.2–38.2) | < .001 |
| Platelet (10^3/μL) | 40 | 51.5 | (32.3–61.8) | 41 | 60.0 | (38.0–83.5) | .033 |
| Protein (g/dL) | 34 | 5.5 | (4.8–6.1) | 32 | 5.4 | (4.6–6.1) | .553 |
| Albumin (g/dL) | 36 | 3.0 | (2.6–3.4) | 34 | 2.7 | (2.4–2.9) | .005 |
| T-bilirubin (mg/dL) | 38 | 0.4 | (0.3–0.6) | 36 | 0.6 | (0.4–0.9) | .013 |
| ALP (IU/L) | 37 | 85.0 | (57.0–163.5) | 35 | 101.0 | (57.0–160.0) | .464 |
| r-GTP (U/L) | 20 | 60.5 | (23.8–139.8) | 18 | 142.0 | (74.3–295.5) | .209 |
| AST (U/L) | 39 | 304.0 | (173.0–487.0) | 40 | 416.0 | (212.5–860.5) | .024 |
| ALT (U/L) | 39 | 99.0 | (57.0–135.0) | 40 | 129.0 | (72.3–229.3) | .026 |
| BUN (mg/dL) | 39 | 16.1 | (11.7–24.1) | 39 | 22.8 | (14.3–29.9) | .021 |
| Serum Cr (mg/dL) | 38 | 0.8 | (0.7–1.2) | 38 | 0.9 | (0.7–1.4) | .483 |
| Amylase | 21 | 136.0 | (86.0–211.5) | 7 | 231.0 | (184.0–351.0) | .345 |
| CK (IU/L) | 26 | 2134.0 | (934.3–2574.3) | 24 | 1470.5 | (866.3–2870.8) | .407 |
| CK-MB (IU/L) | 16 | 5.2 | (3.1–28.7) | 10 | 16.1 | (5.8–24.3) | .500 |
| LDH (IU/L) | 28 | 1100.5 | (823.0–2520.8) | 34 | 2024.0 | (1125.8–3695.0) | .014 |
| CRP (mg/dL) | 32 | 0.5 | (0.1–1.2) | 20 | 0.5 | (0.0–1.7) | .727 |
| Ferritin (ng/mL) | 11 | 3399.4 | (3180.4–16500.0) | 11 | 7325.5 | (2802.3–9504.0) | .593 |
| Serum Na (mEq/L) | 39 | 138.0 | (136.0–140.0) | 35 | 139.0 | (135.0–140.0) | .027 |
| Serum K (mEq/L) | 39 | 3.9 | (3.6–4.2) | 35 | 4.1 | (3.6–4.5) | .224 |
| INR | 28 | 1.1 | (1.0–1.2) | 29 | 1.0 | (1.0–1.1) | .217 |
| aPTT (s) | 28 | 52.3 | (44.2–70.9) | 28 | 44.6 | (34.5–64.9) | .958 |
| Fibrinogen (mg/dL) | 12 | 220.4 | (169.8–248.2) | 15 | 174.7 | (142.2–204.0) | .063 |
Abbreviations: ALC, absolute lymphocyte count; ALP, alkaline phosphatase; ALT, alanine aminotransferase; ANC, absolute neutrophil count; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; BT, body temperature; CK, creatinine kinase; CK-MB, creatine kinase-myocardial band; Cr, creatinine; CRP, c-reactive protein; GCS, Glasgow Coma Scale; Hct, hematocrit; Hgb, hemoglobin; INR, international normalized ratio; K, potassium; LDH, lactate dehydrogenase; Na, sodium; r-GTP, gamma-glutamic transpeptidase; WBC, white blood cell.
a Analysis using Wilcoxon signed-rank test.