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. 2021 Feb 19;15(2):e0009128. doi: 10.1371/journal.pntd.0009128

Table 4. Risk Factors Associated with 30-day Mortality in Patients with SFTS.

Univariate Model Multivariate Modela
Variable HR (95% CI) P Value aHR (95% CI) P Value
Age 1.08 (1.03–1.12) .001 1.10 (1.04–1.17) .001
Arrhythmia 6.23 (2.53–15.38) < .001 4.61 (1.42–14.94) .011
Septic shock/Sepsis 5.32 (2.36–11.99) < .001 4.52 (1.33–15.38) .016
Initial APACHE II score 1.10 (1.06–1.14) < .001 1.08 (1.01–1.15) .033
ICU admission 13.27 (4.02–43.80) < .001 41.90 (4.51–389.16) .001
Initial altered mentation 2.62 (1.21–5.64) .014 -
Initial PT prolongation (INR >1.3) 2.95 (0.88–9.90) .080 -
Mechanical ventilator 8.21 (3.83–17.61) < .001 2.87 (1.01–8.13) .047
CRRT/Hemodialysis 5.74 (2.72–12.11) < .001 4.34 (1.36–13.89) .013

Abbreviations: APACHE, acute physiology and chronic health evaluation; aHR, adjusted hazard ratio; CI, confidence interval; CRRT, continuous renal replacement therapy; DIC, disseminated intravascular coagulation; HR, hazard ratio; ICU, intensive care unit; INR, international normalized ratio; PT, prothrombin time.

a The variables included in the multivariate model were age, arrhythmia, septic shock/sepsis, initial APACHE II score, ICU admission, Initial altered mentation, initial PT prolongation, mechanical ventilator and CRRT/hemodialysis.