Table 2.

Main features of historical KD, KD admitted to an ICU (KD-ICU) and SARS-CoV-2-related inflammatory multisystem syndrome (PIMS/MIS-C)

Characteristics	Historical KD	KD-ICU	PIMS/MIS-C
Demographics
Age, years, median	<5	<5	>7
Mortality, %	∼0	3	2
Clinical signs
Complete KD criteriaa, %	68	62	29
Digestive symptoms/signs	Rare	Frequent	Frequent
Neurologic signs	Rare	Frequent	Frequent
Biological signature
White blood cell count	Increased	Increased	Decreased
Thrombocytopenia	Rare	Frequent	Frequent
CRP level at peak, mg/l	<200	>200	>200
Sodium level, mmol/l	135	132	130
Macrophage activation syndrome	Rare	Rare	Frequent
Abnormal chest X-ray	Rare	Frequent	Frequent
Cardiac complications (acute phase)
Shock syndrome	Rare	Frequent	Frequent
Coronary abnormalities	Frequent	Frequent	Rare
Pericardial effusion, %	18	26	30
Myocarditis, %	3	20	43

^aAssociated with higher frequency of ocular/buccal and cutaneous signs.