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. 2021 Feb 2;8(3):ofab061. doi: 10.1093/ofid/ofab061

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© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Kinetics and magnitude of antiviral antibody responses to SARS-CoV-2. Quantitative analysis of SARS-CoV-2-specific IgG shows that among hospitalized cases with COVID-19, these antibodies increase with time and plateau by ~4 weeks post–symptom onset. Open symbols represent samples that scored negative based on the 2-dimensional ELISA, and closed symbols represent samples that scored positive based on the 2-dimensional ELISA in Figure 3A. Samples obtained from the same study subject are connected by gray lines. Abbreviations: ELISA, enzyme-linked immunosorbent assay; COVID-19, coronavirus disease 2019; IgG, immunoglobulin G; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.