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. 2021 Jan 11:fdaa250. doi: 10.1093/pubmed/fdaa250

Table 3.

Proportion and probability of depression, anxiety and psychological distress in study participants (N = 1978)

Demographic characteristics Depression (PHQ-2) Anxiety (GAD-2) Moderate/severe psychological distress (PHQ-4)
Prevalence, N (%) AOR (95% CI) Prevalence, N (%) AOR (95% CI) Prevalence, N (%) AOR (95% CI)
Sex
 Female 333 (32) Ref 419 (42) 1.27 (1.04–1.56)* 355 (35)* Ref
 Male 445 (45)* 1.42 (1.15–1.74)* 408 (42) Ref 413 (43) 1.08 (0.88–1.33)
Race
 White 570 (39) Ref 622 (43)* Ref 572 (39) Ref
 Black 96 (44) 1.02 (0.72–1.31) 100 (46) 0.89 (0.65–1.21) 97 (45) 0.97 (0.72–1.33)
 Asian 68 (35) 0.86 (0.63–1.26) 63 (33) 0.63 (0.45–0.89)* 60 (31) 0.70 (0.49–0.99)*
 Multiracial 19 (37) 0.72 (0.39–1.45) 16 (35) 0.53 (0.27–1.03) 16 (35) 0.66 (0.34–1.30)
 Other 27 (42) 0.63 (0.36–1.17) 26 (40) 0.45 (0.27–1.00) 23 (35) 0.38 (0.21–0.72)*
Ethnicity
 Non-Hispanic 522 (33)* Ref 569 (36)* Ref 516 (32) Ref
 Hispanic 256 (68) 2.52 (1.92–3.33)* 258 (68) 2.92 (2.21–3.85)* 252 (67)* 2.77 (2.10–3.65)*
Marital status
 Single/ never married 245 (38)* Ref 246 (38)* Ref 236(36)* Ref
 Married 476 (43) 1.14 (0.83–1.54) 511 (46) 1.07 (0.80–1.44) 475 (43) 1.04 (0.78–1.42)
 Engaged/living with a partner 38 (38) 1.03 (0.65–0.163) 48 (48) 1.40 (0.89–2.18) 40 (40) 1.10 (0.69–1.71)
 Divorced/separated/widow 19 (15) 0.57 (0.33–1.04) 22 (18) 0.43 (0.24–0.74)* 17 (14) 0.39 (0.22–0.72)*
Children at home
 No 343 (33)* Ref 360 (35)* Ref 335(32)* Ref
 Yes 435 (47) 1.42 (1.15–1.78)* 467 (50) 1.59 (1.28–1.97)* 433 (47) 1.46 (1.17–1.82)*
Education
 ≤High school 38 (34)* Ref 42 (38)* Ref 36 (32)* Ref
 Some college education 117 (35) 1.21 (0.74–1.97) 102 (31) 0.76 (0.47–1.23) 105 (32) 1.07 (0.66–1.76)
 Bachelor’s degree 431 (45) 1.46 (0.90–2.30) 457 (48) 1.35 (0.87–2.09) 424 (44) 1.47 (0.93–2.31)
 ≥Master’s degree 192 (33) 1.25 (0.77–2.03) 226 (39) 1.27 (0.80–2.03) 203 (35) 1.41 (0.86–2.27)
Current employment status
 Full time 568 (42)* Ref 591 (44)* Ref 563 (42)* Ref
 Part time 116 (37) 0.85 (0.63–1.14) 127 (41) 0.92 (0.70–1.20) 118 (38) 0.88 (0.66–1.17)
 Not employed 94 (30) 1.11 (0.81–1.49) 109 (35) 1.17 (0.87–1.56) 87 (28) 0.93 (0.69–1.27)
Healthcare worker
 No 462 (31)* Ref 506 (34)* Ref 451 (31)* Ref
 Yes 316 (62) 2.40 (1.88–3.06)* 321 (63) 2.02( 1.59–2.56)* 317 (62) 2.39 (1.88–3.06)*
Annual household income
 ≥60 000 318 (32)* Ref 353 (36)* Ref 316 (32)* Ref
 <60 000 460 (46) 1.43 (1.15–1.76)* 474 (48) 1.41 (1.14–1.73)* 452 (45) 1.51 (1.22–1.87)*
Area of residence
 Rural 198 (47)* 1.54 (1.16–2.04)* 197 (47)* 1.36 (1.04–1.79)* 193 (46)* 1.49 (1.12–1.97)*
 Urban 387 (47) 1.81 (1.43–2.29) 412 (50) 1.86 (1.48–2.34) 383 (47) 1.83 (1.45–2.32)
 Suburban 193 (26) Ref 218 (30) Ref 192(26) Ref
Region in USA
 Midwest 209 (32)* 0.78 (0.54–1.08) 242 (36) 0.81 (0.59–1.12) 212 (32)* 0.70 (0.51–0.99)
 South 222 (38) 0.77 (0.53–1.07) 229 (39) 0.75 (0.54–1.04) 214 (36) 0.68 (0.49–.0.94)
 West 237 (51) 1.21 (0.86–1.70) 244 (53) 1.24 (0.89–1.75) 232 (50) 1.11 (0.78–1.55)
 Northeast 101 (40) Ref 105 (42)* Ref 103(41) Ref
Age group
 18–25 years 176 (47)* 3.83 (2.30–6.39)* 175 (47)* 2.89 (1.81–4.62)* 167 (44)* 3.16 (1.91–5.22)*
 26–40 years 396 (45) 3.00 (1.87–4.82) 406 (46) 2.45 (1.59–3.76) 387 (44) 2.89 (1.69–4.28)
 41–60 years 177 (33) 1.86 (1.15–3.01) 207 (38) 1.70 (1.10–2.63) 184 (34) 1.82 (1.13–2.91)
 ≥61 years 29 (16) Ref 39 (21) Ref 30(16) Ref

N (%) indicates the frequency and percentages. AOR indicates adjusted odds ratios computed by adjusting for all the variables in the table with 95% confidence intervals. PHQ-2, GAD-2 and PHQ-4 indicate the levels of severe depression, severe anxiety and moderate-to-severe psychological distress.

* P-values < 0.05.