TABLE I.
Summary of Nucleotide and Non-synonymous Amino Acid Mutations in 59MDW SARS-CoV-2 Sequences
| Gene | Number of nucleotide mutations | Nucleotide mutation frequency | Number of non-synonymous amino acid changes |
|---|---|---|---|
| ORF1a | 44 | 0.404 | 23 |
| ORF1b | 21 | 0.193 | 13 |
| S | 14 | 0.128 | 7 |
| ORF3a | 11 | 0.101 | 9 |
| E | 1 | 0.009 | 1 |
| M | 0 | 0.000 | 0 |
| ORF6 | 1 | 0.009 | 0 |
| ORF7a | 2 | 0.018 | 1 |
| ORF7b | 5 | 0.046 | 4 |
| N | 9 | 0.083 | 4 |
| ORF10 | 1 | 0.009 | 1 |
109 nucleotide mutations were identified in coding regions of SARS-CoV-2 genomes sequenced from 59MDW samples. The mutation frequency per gene was calculated by dividing the number of mutations per gene by number of genome-wide mutations. Column 4 lists the number of non-synonymous amino acid changes per gene.