Table 5.

ZAS and Syn-SNV Removing CpG Dinucleotides Preceded by ZAP-Binding Motifs across the SARS-CoV-2 Genome.

		CpGext			CpGext↓SNV
	L	Num	/L (%)	ZAS/L (%)	Num	/CpG↓SNV (%)
5′UTR	211	2	1.4	2	3	16
		With counts			88	0.2
N	1,260	12	1.0	4	10	42
		With counts			1,587	71
ORF7a	336	2	0.6	3	1	20
		With counts			17	7
ORF1a	13,203	25	0.2	1	15	17
		With counts			726	18
ORF1b	8,088	16	0.2	1	9	19
		With counts			317	4
S	3,822	3	0.1	0.3	1	6
		With counts			25	4
ORF3a	828	4	0.5	2	0	0
		With counts			0	0
M	669	2	0.3	2	0	0
		With counts			0	0

Note.—The table gives for each region with at least one motif of the form CnxGxCG with $n=4,5,6,7$, or 8 (CpGext) the length L, the number of CpGext and their number per unit length, the ZAS for unit length (ZAS/L), the number of syn-SNV removing a CpG preceding by an extended motif (CpGext↓SNV), and their fraction with respect to the total number of CpG-decreasing syn-SNV. Additional informations are given in supplementary table SI.2, Supplementary Material online. Numbers and percentage of CpGext↓SNV are given with and without taking into account SNV counts. ORFs are sorted according to the density of CpGext removing SNV (CpGext↓SNV/L). On 5′ and 3′UTRs, there are no synonymous restriction on SNV.