Table 1.
Change in the number of prescriptions per 1000 registered patients in England according to the seasonal adjusted segmented regression models considering as intervention the declaration of COVID-19 as pandemic in March 2020.
| Coefficients | 95%CI | P-value | |
|---|---|---|---|
| ICS prescriptions per 1000 patientsa | |||
| Intercept | 28.8 | 27.8 to 29.8 | <0.0001 |
| Baseline trend | −0.1 | −0.1 to −0.01 | 0.017 |
| Level change after the intervention | 8.0 | 5 to 11 | <0.0001 |
| Trend changes after the intervention | −1.1 | −1.7 to −0.6 | <0.0001 |
| Prednisolone prescriptions per 10 00 patients | |||
| Intercept | 10.3 | 9.9 to 10.7 | <0.0001 |
| Baseline trend | −0.01 | −0.03 to 0.03 | 0.11 |
| Level change after the intervention | 1.3 | −0.1 to 2.2 | 0.08 |
| Trend change after the intervention | −0.4 | −0.6 to −0.1 | 0.002 |
| Antibiotics prescriptions per 10 00 patientsb | |||
| Intercept | 20.8 | 19.8 to 21.8 | <0.0001 |
| Baseline trend | −0.1 | −0.2 to −0.1 | <0.0001 |
| Level change after the intervention | 0.6 | −2.2 to 3.3 | 0.7 |
| Trend change after the intervention | −0.5 | −0.1 to 0.01 | 0.053 |
aFluticasone Propionate, Budesonide, Beclomethasone Dipropionate, Ciclesonide, Mometasone Furoate.
bAmoxicillin, Doxycycline, Co-Amoxiclav, Erythromycin.