Table 1.
Royal Free Hospital |
Barnet Hospital |
|||||
---|---|---|---|---|---|---|
Diagnosis | CAP (n = 106) | COVID-19 (n = 619) | P value | CAP (n = 169) | COVID-19 (n = 181) | P value |
Chest radiograph, n (%)a | ||||||
Lobar consolidation | 106 (100) | 4 (0.6) | – | 169 (100) | 0 (0%) | – |
CVXC0 | 62 (10.0) | 22 (12.2) | ||||
CVCX1 | 281 (45.3) | 71 (39.2) | ||||
CVCX2 | 136 (22.0) | 36 (19.9) | ||||
CVCX3 | 17 (2.7) | 5 (2.8) | ||||
Ungraded | 123 (19.9) | 47 (26.0) | ||||
Male, n (%) | 50 (47) | 386 (62) | 0.0037 | 81 (47.9) | 104 (57.5) | 0.0865 |
Age, years, median (range) | 72 (19–99) | 68 (18–100) | 0.1401 | 74 (18–98) | 71 (29–98) | 0.0633 |
Ethnicity, n (%) | 0.0007 | 0.0335 | ||||
White | 60 (57) | 250 (40) | 128 (76) | 115 (64) | ||
Asian | 23 (22) | 83 (13) | 11 (7) | 26 (14) | ||
Black | 6 (6) | 69 (11) | 1 (1) | 11 (6) | ||
Mixed | 2 (2) | 7 (1) | 0 (0) | 2 (1) | ||
Other/unknown | 15 (14) | 210 (34) | 29 (17) | 27 (15) | ||
Charlson index co- morbidities n (%) | <0.0001 | 0.0206 | ||||
0 | 18 (17) | 243 (39) | 51 (30) | 81 (45) | ||
1 | 33 (31) | 190 (31) | 51 (30) | 58 (32) | ||
2 | 28 (26) | 109 (18) | 35 (21) | 23 (13) | ||
3+ | 27 (25) | 77 (13) | 32 (19) | 19 (10) | ||
Patients with microbiological identification of bacteria, n (%) | 15 (14.2) | 26 (4.2) | 0.0003 | 15 (8.9) | 10 (5.5) | 0.2992 |
Microbiology results, n (%) | ||||||
Sputum | 6 (5.7) | 8 (1.3) | 2 (1.2) | 5 (2.8) | ||
Blood | 2 (1.9) | 12 (1.9) | 6 (3.6) | 5 (2.8) | ||
Urine Ag | 4 (3.8) | 3 (0.5) | 8 (4.7) | 0 (0.0) | ||
Mycoplasma PCR | 5 (4.7) | 3 (0.5) | 0 (0.0) | 0 (0.0) | ||
Blood samples collected 48–72 h into admission, n (%) | 53 (50.0) | 331 (53.5) | 99 (58.6) | 60 (33.1) |
P values represent comparisons between CAP and COVID-19 and each hospital site. Comparisons between the cohorts at each hospital site were performed by Mann–Whitney test for age, by Fisher’s exact test for gender, and by Chi-square test for ethnicity, Charlson co-morbidities and microbiological results. P values represent comparisons between CAP and COVID-19 and each hospital site.
Chest radiograph codes for COVID-19 patients based on British Society of Thoracic Imaging guidelines: CVCX0 = Normal; CVCX1 = Classic for COVID-19; CVCX2 = Indeterminate for COVID-19; CVCX3 = Non-COVID-19.