Table 3.
Discriminatory performance of WCC and ΔCRP cut-offs for diagnosis of CAP in RFH patients
| Cut-offa | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) | Positive likelihood ratio | Negative likelihood ratio |
|---|---|---|---|---|---|---|
| WCC > 8.2 | 79.2 | 58.8 | 24.6 | 94.4 | 1.92 | 0.35 |
| WCC > 9.4 | 69.8 | 70.0 | 28.2 | 93.2 | 2.32 | 0.43 |
| CRP > 65 | 84.9 | 33.2 | 17.7 | 92.9 | 1.27 | 0.45 |
| CRP > 160 | 49.1 | 71.6 | 22.6 | 89.2 | 1.73 | 0.71 |
| WCC > 8.2 AND CRP > 65 | 69.8 | 70.3 | 28.5 | 93.2 | 2.35 | 0.43 |
| WCC > 8.2 OR CRP > 65 | 94.3 | 21.7 | 16.9 | 95.8 | 1.21 | 0.26 |
| ΔCRP<−15 | 62.3 | 75.0 | 29.7 | 92.2 | 2.50 | 0.50 |
| ΔCRP < 0 | 73.6 | 65.2 | 26.4 | 93.6 | 2.11 | 0.41 |
| WCC > 8.2 AND ΔCRP < 0 | 62.3 | 80.8 | 35.4 | 92.6 | 3.25 | 0.47 |
| WCC > 8.2 OR ΔCRP < 0 | 90.6 | 43.1 | 21.2 | 96.4 | 1.59 | 0.22 |
Populations included were all patients admitted >48 h for CAP (n = 53) and MR− COVID-19 (n = 313). aWCC values represent cell numbers ×106/mL. CRP values represent concentrations in mg/L.