Table 3.
Logistic regression analysis of risk factors for mortality in all HD patients
| OR (95% CI) | P-value | |
|---|---|---|
| Demographic parameters | ||
| Age ≥70 years | 1.55 (1.08–2.23) | 0.017 |
| Sex (male) | 1.44 (1.02–2.04) | 0.039 |
| BMI | 1.17 (0.97–1.42) | 0.106 |
| Diabetes mellitus | 1.18 (0.84–1.66) | 0.352 |
| Employed/working | 1.24 (0.9–1.71) | 0.189 |
| Separated, divorced or widow | 1.29 (0.82–2.01) | 0.268 |
| Laboratory parameters before infection | ||
| 25(OH) vitamin D (ng/mL) | 0.93 (0.68–1.27) | 0.648 |
| Hemoglobin (1 g/dL) | 0.91 (0.79–1.05) | 0.213 |
| Albumin (g/dL) | 0.97 (0.93–1.02) | 0.253 |
| Inorganic phosphorus (mg/dL) | 0.96 (0.86–1.07) | 0.453 |
| Calcium (mg/dL) | 1.02 (0.84–1.23) | 0.879 |
| Intact PTH (pg/mL) | 1.05 (0.81–1.36) | 0.732 |
| Comorbidities | ||
| Glomerulonephritis | 0.8 (0.48–1.31) | 0.367 |
| Ischemic heart diseases | 1.41 (0.99–2.00) | 0.048 |
| Pulmonary diseases | 0.74 (0.49–1.13) | 0.168 |
| Neoplasms | 1.27 (0.81–1.98) | 0.296 |
| Mental and behavioural disorders | 1.11 (0.71–1.74) | 0.648 |
| Connective tissue disease | 4.22 (0.74–23.97) | 0.105 |
| Other endocrine disease | 1.41 (0.89–2.23) | 0.143 |
| Dialysis related parameters | ||
| AV fistula | 0.6 (0.43–0.84) | 0.003 |
| Time on dialysis (month) | 1 (1–1.01) | 0.015 |
| Medication | ||
| ACE inhibitors | 0.86 (0.57–1.3) | 0.474 |
| Calcium antagonists | 1 (0.74–1.35) | 0.991 |
| Digitalis | 1.27 (0.36–4.43) | 0.708 |
| Nitrates | 1.18 (0.77–1.81) | 0.453 |
| Antidepressant | 1.12 (0.67–1.86) | 0.678 |
| Anxiolytic or hypnotic | 1.72 (1.12–2.64) | 0.014 |
| Statins | 1.08 (0.77–1.52) | 0.646 |
ORs were calculated by logistic regression models, adjusted for all variables with a P < 0.2 in the univariate analyse, country and the following variables, considered to be of clinical relevance for the predicted outcomes: age, gender, BMI, diabetes mellitus, treatment with active vitamin D, hemoglobin, serum inorganic phosphorus, calcium and intact PTH.