Table 1.
The association of concordant genes in GO terms and GO pathways and the proportional P-values
| Category | GO ID | Term | P-value | Genes |
|---|---|---|---|---|
| GO biological process | GO:0030593 | Neutrophil Chemotaxis | 6.563(e-10) | SAA1, S100A12, S100A9, S100A8 |
| GO:0071621 | Granulocyte Chemotaxis | 8.230(e-10) | SAA1, S100A12, S100A9, S100A8 | |
| GO:1990266 | Neutrophil Migration | 9.506(e-10) | SAA1, S100A12, S100A9, S100A8 | |
| GO:0050832 | Defense response to fungus | 1.018(e-8) | S100A12, S100A9, S100A8 | |
| GO:0050727 | Regulation of inflammatory response | 6.777(e-8) | SAA1, S100A12, S100A9, S100A8 | |
| GO:0051091 | Positive regulation of sequence-specific DNA-binding transcription factor activity | 1.915(e-7) | EDN1, S100A12, S100A9, S100A8 | |
| GO:0050729 | Positive regulation of inflammatory response | 9.257(e-7) | S100A12, S100A9, S100A8 | |
| GO:0031349 | Positive regulation of defense response | 9.647(e-7) | S100A12, S100A9, S100A8 | |
| GO:0070486 | Leukocyte aggregation | 0.000001574 | S100A9, S100A8 | |
| GO:0032103 | Positive regulation of response to external stimulus | 0.000001745 | S100A12, S100A9, S100A8 | |
| GO molecular function | GO:0050786 | RAGE receptor binding | 1.259(e-9) | S100A12, S100A9, S100A8 |
| GO:0035325 | Toll-like receptor binding | 0.000002697 | S100A9, S100A8 | |
| GO:0005509 | Calcium ion binding | 0.00005490 | S100A12, S100A9, S100A8 | |
| GO:0008270 | Zinc ion binding | 0.00006592 | S100A12, S100A9, S100A8 | |
| GO:0046914 | Transition metal ion binding | 0.0001507 | S100A12, S100A9, S100A8 | |
| GO:0046872 | Metal ion binding | 0.0002040 | S100A12, S100A9, S100A8 | |
| GO:0008017 | Microtubule binding | 0.001383 | S100A9, S100A8 | |
| GO:0015631 | Tubulin binding | 0.002348 | S100A9, S100A8 | |
| GO:0005507 | Copper ion binding | 0.01224 | S100A12 | |
| GO cellular component | GO:0060205 | Cytoplasmic vesicle lumen | 2.453(e-8) | SAA1, S100A12, S100A9, S100A8 |
| GO:0071682 | Endocytic vesicle lumen | 0.005388 | SAA1 | |
| GO:0005881 | Cytoplasmic microtubule | 0.01135 | SAA1 | |
| GO:0034774 | Secretory granule lumen | 0.00007614 | S100A12, S100A9, S100A8 | |
| GO:0045111 | Intermediate filament cytoskeleton | 0.02111 | S100A8 | |
| GO:0005856 | Cytoskeleton | 0.0003296 | S100A12, S100A9, S100A8 | |
| GO:0030139 | Endocytic vesicle | 0.03197 | SAA1 | |
| GO:0005874 | Microtubule | 0.06138 | SAA1 |