Figure 2.

Unfolded protein response pathway. The signalling flow in a UPR pathway is shown schematically. From left to right, the panels represent ATF6, PERK and IRE1 axis of the UPR, respectively. Role of ncRNA at different stages are highlighted with arrows. (eIF2α- Eukaryotic transcription Initiation Factor 2 α, S1P- Site 1 protease, S2P- Site 2 protease, BCL2- B Cell Lymphoma 2). The acronyms for rest of the genes are included in the manuscript.