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. 2021 Jan 27:aqaa274. doi: 10.1093/ajcp/aqaa274

Table 3.

Clinical and Laboratory Data, Including Parameters of the HScore for Deceased Patients Who Tested Positive for COVID-19

Patient
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Clinical data
 Age, y 76 76 59 60 66 56 76 33 75 32 72 48 40 87 89 45 >89 85 44 57
 Sex F M M F M M F M F F M M M M F F M M F M
 Race/ethnicity W W W H H H W W H H W H H W W B W W W H
 BMI 38.9 35.4 34.4 35.3 37.1 31.6 32.5 28.6 31.7 61.0 21.5 30.6 45.8 27.1 23.0 69.3 19.8 32.8 44.8 30.0
 Known coinfection No No No Yes No Yes Yes Yes No No NA Yes No No No NA NA Yes No No
CBC values, initial and final
 WBC, initial, × 109/L 7.69 10.02 9.30 5.43 10.41 4.66 15.8 8.81 20.24 18.66 NA 8.18 7.62 3.32 24.38 NA NA 7.16 20.12 7.43
 WBC, final, × 109/L 8.00 19.11 57.43 16.54 20.17 11.95 16.08 18.96 18.17 30.87 NA 11.55 39.19 7.26 24.38 NA NA 17.21 29.4 16.48
 HGB, initial, g/dL 13.9 14.8 13.5 13.3 13.4 16.5 17.9 12.5 16.0 10.1 NA 11.8 15.3 10.9 14.2 NA NA 13.9 20.3 14.1
 HGB, final, g/dL 12.8 11.3 9.9 11.8 11.4 9.7 14.9 10.9 13.3 11.4 NA 11.3 11.4 9.9 14.2 NA NA 11.1 21.2 8.2
 HCT, initial, L/L 43.2 42.2 38.3 39.8 41.2 50.1 56.9 37.5 50.1 32.7 NA 39.5 44.7 33.6 42.4 NA NA 41.8 64.1 42.1
 HCT, final, L/L 38.7 35.1 31.4 35.5 34.9 32.4 49.0 33.5 41.7 37.5 NA 38.7 35.2 30.9 42.4 NA NA 34.0 66.1 28.1
 PLT, initial, × 109/L 140 229 139 158 261 71 276 115 145 337 NA 472 189 205 399 NA NA 97 336 235
 PLT, final, × 109/L 168 520 257 33 225 147 218 128 67 213 NA 93 249 283 399 NA NA 240 297 309
 ANC, initial, × 109/L 6.15 8.88 8.66 4.18 5.05 3.85 15.1 6.29 16.55 16.05 NA 6.58 6.27 1.65 10.11 NA NA 6.34 18.03 5.81
 ANC, final, × 109/L 7.33 15.35 42.50 15.68 16.72 NA 14.78 15.32 16.84 25.62 NA 7.53 34.1 6.04 10.11 NA NA 14.16 NA 13.12
 ALC, initial, × 109/L 1.27 0.09 0.48 0.93 4.21 0.48 0.55 0.94 1.84 1.31 NA 0.65 0.83 0.97 13.5 NA NA 0.57 0.71 1.03
 ALC, final, × 109/L 0.63 1.03 4.82 0.58 1.55 NA 0.58 1.37 0.79 3.42 NA 3.34 3.41 0.74 13.5 NA NA 1.22 NA 1.52
HScore parameters
 Underlying immunosuppression Yes No No No No Yes No No No No Yes No No No No No No No No No
 Temperature, maximum, °C 39.3 39.6 37 40.1 39.1 42.4 37.5 40.4 37.7 39.5 NA 40 39.9 37.2 37.5 NA NA 38.1 37.8 39.9
 Organomegaly No No No No No No No No No No No No No No No No No No No No
 Cytopenia, lineagesa 0 0 0 1 0 3 0 1 1 0 NA 1 0 1 0 NA NA 1 0 1
 Ferritin, ng/mL 675 758 1,619 25,018 5,182 7,689 4,398 798 942 413 NA 2,768 3,961 351 1,064 NA NA 464 690 664
 Triglycerides, mmoles/L NA 4 8 5 13 14 NA NA 2 14 NA 5 6 1 NA NA NA 6 0 3
 Fibrinogen, g/L NA 12.41 13.35 6.06 10.08 6.51 NA 6.41 5.66 7.1 NA 7.61 11.2 8.55 NA NA NA 9.63 7.33 6.54
 AST, IU/L 42 121 229 1,977 1,553 206 72 68 180 53 NA 87 205 26 NA NA NA 71 42 306
 Hemophagocytosis Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes NAb Yes Yes Yes Yes Yes Yes
 HScore 105 147 118 217 186 269 89 103 98 132 53 202 202 0 35 35 35 54 54 147

ALC, absolute lymphocyte count; ANC, absolute neutrophil count; AST, glutamic oxaloacetic transaminase; B, Black; H, Hispanic; HCT, hematocrit; HGB, hemoglobin; NA, not available; W, White.

aDefined as hemoglobin <9.2 g/dL, WBC <5 × 109/L, platelets <110 × 109/L; evaluated over the course of hospitalization.

bMarrow too necrotic for evaluation.