Table 2.
Comparison of perioperative biochemical characteristics between intermediate- (100 mCi) and high-dose (150 mCi) groups before and after propensity score matching.
| Before matching | p value | After matching | p value | |||
|---|---|---|---|---|---|---|
| 100 mCi (n = 1146) | 150 mCi (n = 302) | 100 mCi (n = 1146) | 150 mCi (n = 302) | |||
| Pre-op. TSH (mIU/L) | 2.9 ± 10.9 | 2.2 ± 1.8 | 0.276 | 2.1 ± 1.5 | 2.2 ± 1.8 | 0.549 |
| Pre-op. serum Tg (ng/mL) | 30.9 ± 75.6 | 39.7 ± 89.4 | 0.086 | 38.7 ± 99.9 | 39.9 ± 92.4 | 0.885 |
| ≤1 | 114 (9.9%) | 30 (9.9%) | 1.000 | 30 (10.9%) | 28 (10.1%) | 0.890 |
| >1 | 1032 (90.1%) | 272 (90.1%) | 246 (89.1%) | 248 (89.9%) | ||
| ≤10 | 505 (44.1%) | 109 (36.1%) | 0.013 | 111 (40.2%) | 99 (35.9%) | 0.335 |
| >10 | 641 (55.9%) | 193 (63.9%) | 165 (59.8%) | 177 (64.1%) | ||
|
| ||||||
| Pre-op. serum TgAb (IU/mL) | 113.7 ± 595.9 | 207.0 ± 884.2 | 0.031 | 170.5 ± 889.8 | 144.3 ± 569.0 | 0.681 |
| Negative | 922 (80.5%) | 235 (77.8%) | 0.333 | 225 (81.5%) | 216 (78.3%) | 0.396 |
| Positive | 224 (19.5%) | 67 (22.2%) | 51 (18.5%) | 60 (21.7%) | ||
|
| ||||||
| Post-RAI serum Tg (ng/mL) | 3.8 ± 12.5 | 9.8 ± 41.2 | <0.001 | 5.3 ± 13.7 | 6.7 ± 15.9 | 0.263 |
| ≤1 | 665 (58.0%) | 154 (51.0%) | 0.031 | 141 (51.1%) | 144 (52.2%) | 0.865 |
| >1 | 481 (42.0%) | 148 (49.0%) | 135 (48.9%) | 132 (47.8%) | ||
| ≤10 | 1048 (91.4%) | 246 (81.5%) | <0.001 | 245 (88.8%) | 229 (83.0%) | 0.066 |
| >10 | 98 (8.6%) | 56 (18.5%) | 31 (11.2%) | 47 (17.0%) | ||
|
| ||||||
| Post-RAI serum TgAb (IU/mL) | 31.1 ± 100.9 | 64.2 ± 324.8 | 0.003 | 44.5 ± 163.9 | 35.6 ± 133.3 | 0.484 |
| Negative | 1067 (93.1%) | 272 (90.1%) | 0.086 | 252 (91.3%) | 252 (91.3%) | 1.000 |
| Positive | 79 (6.9%) | 31 (9.9%) | 24 (8.7%) | 241 (8.7%) | ||
Data are expressed as the patient's number (%) or mean ± SD. A statistically significant difference was defined as p < 0.05. Negative TgAb, TgAb <60 IU/mL; positive TgAb, TgAb ≥60 IU/mL. Abbreviation: TSH, thyroid-stimulating hormone; pre-op, preoperative; post-RAI, after radioactive iodine therapy; Tg, thyroglobulin; TgAb, thyroglobulin antibody.