FIGURE 6.

Eriodictyol protects the mice from S. aureus-induced pneumonia. (A) Effect of eriodictyol treatment on the survival of mice (n = 10) infected with a lethal dose of S. aureus. Mock vs. eriodictyol, **P < 0.01; log-rank test. (B) Effect of eriodictyol treatment (100 mg/kg) on the bacterial load in the lungs of mice (n = 5). **P < 0.01, ***P < 0.001 vs. the WT group; Mann-Whitney test, two-tailed. Horizontal bars represent the mean values. (C) Histopathology of the lung (H&E staining) of mice treated with or without eriodictyol (100 mg/kg/d). The animal data were obtained in two separate experiments (magnification: 400×; scale bar, 50 μm).