Table 2.
Neurodevelopmental outcome.
| Neurodevelopmental outcome | HIE without hypothermia (n = 28) | HIE with hypothermia (n = 21) | p-value* |
|---|---|---|---|
| Intelligence | |||
| Total intelligence quotient, mean (SD) | 94.3 (15.4) | 94.1 (17.1) | 0.96 |
| Verbal intelligence quotient, mean (SD) | 97.7 (12.8) | 98.8 (15.5) | 0.78 |
| Performance intelligence quotient, mean (SD) | 94.0 (15.7) | 90.3 (18.4) | 0.46 |
| Processing Speed, mean (SD) | 102.3 (15.9) | 91.1 (14.2) | 0.02 |
| Memory | |||
| Verbal long-term memory-immediate recall, mean decile score (SD) | 4.7 (3.0) | 2.2 (2.3) | 0.001** |
| Verbal long-term memory-delayed recall, mean decile score corrected for age (SD) | 3.5 (2.7) | 2.2 (2.2) | 0.03 |
| Verbal Working Memory, mean norm score (SD) | 9.3 (4.1) | 9.3 (2.8) | 0.97 |
| Visual-spatial Working Memory, mean t-score (SD) | 47.7 (9.5) | 48.5 (14.1) | 0.84 |
| Visual-spatial long-term memory-direct recall, mean t-score (SD) | 39.2 (13.8) | 32.7 (15.2) | 0.12 |
| Visual-spatial long-term memory-delayed recall, mean t-score (SD) | 37.0 (11.9) | 31.1 (13.9) | 0.11 |
| Attention | |||
| Sustained attention, mean (SD) | 8.2 (3.1) | 8.7 (3.4) | 0.55 |
| Selective attention, mean (SD) | 9.8 (2.4) | 9.4 (2.6) | 0.59 |
| Motor outcome | |||
| Total composite score, mean (SD) | 48.6 (11.1) | 43.0 (9.0) | 0.06 |
| Fine Manual Control standard score, mean (SD) | 45.5 (9.9) | 41.2 (9.3) | 0.09 |
| Manual Coordination standard score, mean (SD) | 48.9 (8.5) | 45.0 (11.1) | 0.19 |
| Body coordination standard score, mean (SD) | 43.0 (8.5) | 40.3 (9.2) | 0.32 |
| Strength and agility standard score, mean (SD) | 57.6 (9.9) | 52.6 (8.2) | 0.07 |
*For the outcomes of the neuropsychological assessments, after correction for multiple comparison, p-values < 0.004 were statistically significant. For the motor outcome, p-values < 0.01 were statistically significant.
**Statistically significant.