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. 2021 Mar 3;11:5017. doi: 10.1038/s41598-021-83982-8

Table 4.

Multivariable logistic regression models for different neuropsychological tests with MB and with total hippocampal volume.

Outcome measure Model with MB Odds ratio (95%CI) Model with hippocampus Odds ratio (95%CI)
Cognition
Total intelligence quotient MB atrophy 35.00 (5.53–221.39) Hippocampus 0.19 (0.07–0.55)
Verbal intelligence quotient Grey matter 0.98 (0.97–1.00) White matter 0.97 (0.95–1.00)
MB atrophy 7.26 (1.1–48.33)
Performance intelligence quotient MB atrophy 32.50 (5.12–206.16) Hippocampus 0.19 (0.06–0.53)
Processing Speed MB atrophy 3.75 (0.90–15.66) Hippocampus 0.48 (0.23–0.99)
Memory
Verbal long-term memory-immediate recall MB atrophy 50.00 (5.40–463.20) Hippocampus 0.24 (0.09–0.65)
Lateral ventricles 1.2 (0.99–1.40)
Verbal long-term memory-delayed recall MB atrophy n/aa Hippocampus 0.16 (0.05–0.47)
Grey matter 1.02 (1.00–1.03)
Verbal Working Memory Grey matter 0.99 (0.98–1.00) Grey matter 0.99 (0.98–1.00)
Lateral ventricles 1.11 (0.99–1.26) Lateral ventricles 1.11 (0.99–1.26)
Visual-spatial Working Memory n.s n.s n.s n.s
Visual-spatial long-term memory direct recall MB atrophy n/aa Hippocampus 0.33 (0.14–0.77)
Visual-spatial long-term memory delayed recall MB atrophy n/aa Hippocampus 0.21 (0.07–0.63)

aNo Odds Ratio’s could be calculated, because none of the infants with atrophy of the MB had a normal outcome.