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. 2021 Feb 18;12:609884. doi: 10.3389/fimmu.2021.609884

Figure 6.

Figure 6

IFNγ ELISpot responses observed in HIV+ Volunteers. (A)—Number of total ELISpot responses observed in volunteers whose transmitted founder proteome sequence was included within the in-silico prediction (Seq In: N = 10) and volunteers whose transmitted founder proteome sequence was not included within the in-silico prediction (Seq Out: N = 13). Shapiro-Wilk values Seq In: W = 0.7887, p = 0.0008. Seq Out: W = 0.8976, p = 0.0315. Mann-Whitney test, p = 0.6215. (B)—Correlation of total number of ELISpot responses in volunteers whose transmitted founder proteome sequence was included within the in-silico prediction against the order of priority the sequence was predicted to occur (Spearman Correlation; r = 0.1356, p = 0.2209). (C)—Correlation of total number of ELISpot responses in volunteers whose transmitted founder proteome sequence was included within in silico prediction against the % coverage each epitope represented (Spearman Correlation; r = 0.2695, p = 0.0357).