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. 2021 Mar 3;7:20. doi: 10.1038/s41522-021-00191-x

Table 3.

Baseline characteristics of patients according to mortality status before matching.

Characteristic Dead (n = 15) Alive (n = 94) P Value
Age (years) 74 ± 10 68 ± 10 0.031
Male sex, n (%) 7 (46.7%) 50 (53.2%) 0.638
DM, n (%) 6 (40.0%) 48 (51.1%) 0.426
CVD, n (%) 9 (60.0%) 41 (43.6%) 0.237
Charlson comorbidity index
1–2 0 (0.0%) 1 (1.1%)
3–4 0 (0.0%) 20 (21.3%) 0.126
≥5 15 (100.0%) 73 (77.7%)
Dialysis vintage (years) 7.0 (6.0–9.0) 8.0 (4.1–11.1) 0.747
Dialysis access type
Arteriovenous fistula 10 (66.7%) 86 (91.5%)
Arteriovenous graft 4 (26.7%) 8 (8.5%) 0.004
Central venous catheter 1 (6.7%) 0 (0.0%)
BMI (kg/m2) 22.6 ± 3.3 24.0 ± 3.5 0.146
FTI (kg/m2) 8.7 ± 4.7 9.7 ± 3.9 0.363
LTI (kg/m2) 13.4 ± 3.0 13.5 ± 3.2 0.886
BF (%) 27.2 ± 12.5 29.2 ± 9.8 0.469
Overhydration (%) 5.8 (−5.4–12.4) 4.1 (−2.6–10.0) 0.829
SGA score 5.5 (5.0–7.0) 6.0 (6.0–7.0) 0.082
PASE score 9 (0–68) 51 (23–67) 0.080
Medication
PPI, n (%) 1 (7.1%) 9 (9.6%) 0.770
Calcium carbonate, n (%) 10 (71.4%) 79 (84.0%) 0.248
CCB, n (%) 6 (42.9%) 45 (47.9%) 0.726
β-blocker, n (%) 7 (50.0%) 44 (46.8%) 0.823
RAASi, n (%) 4 (28.6%) 32 (34.0%) 0.685
Dietary intake (servings/day)
Vegetables 1.8 (0.4–2.7) 2.3 (1.6–3.3) 0.059
Fruits 0.7 (0.2–1.0) 0.7 (0.3–1.2) 0.559
Meat 0.6 (0.0–1.3) 0.7 (0.4–1.3) 0.353
Laboratory parameters
Kt/V 1.6 ± 0.6 1.8 ± 0.3 0.142
nPNA (g/kg/day) 1.1 ± 0.2 1.2 ± 0.3 0.164
Albumin (g/dl) 3.8 ± 0.3 4.0 ± 0.4 0.148
Fasting glucose (mg/dl) 112 (97–147) 109 (99–147) 0.847
Total cholesterol (mg/dl) 135 (124–152) 158 (143–186) 0.012
LDL (mg/dl) 74 (63–87) 90 (72–111) 0.016
Triglycerides (mg/dl) 88 (58–192) 106 (75–154) 0.305
Calcium (mmol/l) 9.2 ± 0.8 9.3 ± 0.8 0.544
Phosphorus (mg/dl) 4.9 ± 1.5 5.3 ± 1.3 0.389
iPTH (pg/ml) 183 (25–467) 345 (179–517) 0.249
CRP (mg/dl) 0.30 (0.14–0.88) 0.27 (0.15–0.62) 0.556
IL-6 (pg/ml) 16.87 (11.57–34.59) 7.15 (4.90–14.67) 0.002
TNF-α (pg/ml) 7.15 (1.86–18.67) 3.40 (1.27–6.54) 0.040

BF body fat, BMI body mass index, CCB calcium channel blocker, CRP C-reactive protein, CVD cardiovascular disease, DM diabetes mellitus, FTI fat tissue index, IL-6 interleukin-6, iPTH intact parathyroid hormone, LDL low-density lipoprotein, LTI lean tissue index, nPNA normalized protein nitrogen appearance, PASE the Physical Activity Scale for the Elderly, PPI proton pump inhibitor, RAASi renin-angiotensin-aldosterone system inhibitor, SGA subjective global assessment, TNF-α tumor necrosis factor-α.