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. 2021 Mar 3;7:20. doi: 10.1038/s41522-021-00191-x

Table 4.

Baseline characteristics of patients according to mortality status after matching.

Characteristic Dead (n = 14) Alive (n = 56) P Value
Age (years) 73 ± 9 71 ± 9 0.419
Male sex, n (%) 7 (50.0%) 28 (50.0%) 1.000
DM, n (%) 6 (42.9%) 32 (57.1%) 0.337
CVD, n (%) 9 (64.3%) 28 (50.0%) 0.338
Charlson comorbidity index
1–2 0 (0.0%) 0 (0.0%)
3–4 0 (0.0%) 8 (14.3%) 0.133
≥5 14 (100.0%) 48 (85.7%)
Dialysis vintage (years) 7.0 (5.5–9.8) 8.0 (4.0–11.3) 0.797
Dialysis access type
Arteriovenous fistula 9 (64.3%) 51 (91.1%)
Arteriovenous graft 4 (28.6%) 5 (8.9%) 0.015
Central venous catheter 1 (7.1%) 0 (0.0%)
BMI (kg/m2) 22.4 ± 3.3 23.9 ± 3.5 0.134
FTI (kg/m2) 8.3 ± 4.5 9.6 ± 4.3 0.300
LTI (kg/m2) 13.6 ± 3.1 13.3 ± 3.4 0.813
BF (%) 26.1 ± 12.3 28.9 ± 10.7 0.405
Overhydration (%) 6.6 (−5.1–13.2) 6.1 (−0.9–10.0) 0.912
SGA score 5.0 (5.0–6.5) 6.0 (6.0–7.0) 0.032
PASE score 17 (2–73) 54 (22–71) 0.204
Medication
PPI, n (%) 1 (7.7%) 4 (7.1%) 0.945
Calcium carbonate, n (%) 9 (69.2%) 45 (80.4%) 0.381
CCB, n (%) 6 (46.2%) 28 (50.0%) 0.803
β-blocker, n (%) 7 (53.8%) 26 (46.4%) 0.630
RAASi, n (%) 4 (30.8%) 21 (37.5%) 0.649
Dietary intake (servings/day)
Vegetables 1.9 (0.3–2.7) 2.3 (1.8–3.2) 0.083
Fruits 0.7 (0.2–1.0) 0.6 (0.3–1.2) 0.497
Meat 0.6 (0.0–1.3) 0.7 (0.4–1.2) 0.696
Laboratory parameters
Kt/V 1.6 ± 0.6 1.8 ± 0.3 0.128
nPNA (g/kg/day) 1.1 ± 0.2 1.2 ± 0.3 0.095
Albumin (g/dl) 3.8 ± 0.3 4.0 ± 0.3 0.202
Fasting glucose (mg/dl) 115 (100–157) 111 (101–156) 0.877
Total cholesterol (mg/dl) 138 (122–155) 157 (144–187) 0.033
LDL (mg/dl) 75 (68–87) 89 (69–111) 0.053
Triglycerides (mg/dl) 89 (59–193) 101 (68–153) 0.681
Calcium (mmol/l) 9.1 ± 0.8 9.4 ± 0.9 0.354
Phosphorus (mg/dl) 4.9 ± 1.5 5.1 ± 1.3 0.503
iPTH (pg/ml) 166 (24–494) 295 (185–577) 0.154
CRP (mg/dl) 0.36 (0.14–1.07) 0.26 (0.15–0.59) 0.436
IL-6 (pg/ml) 17.50 (10.59–34.95) 6.86 (5.06–14.76) 0.006
TNF-α (pg/ml) 7.07 (1.71–24.07) 2.53 (0.50–5.06) 0.026

BF body fat, BMI body mass index, CCB calcium channel blocker, CRP C-reactive protein, CVD cardiovascular disease, DM diabetes mellitus, FTI fat tissue index, IL-6 interleukin-6, iPTH intact parathyroid hormone, LDL low-density lipoprotein, LTI lean tissue index, nPNA normalized protein nitrogen appearance, PASE the Physical Activity Scale for the Elderly, PPI proton pump inhibitor, RAASi renin-angiotensin-aldosterone system inhibitor, SGA subjective global assessment, TNF-α tumor necrosis factor-α.