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. 2021 Feb 26;7(2):e06367. doi: 10.1016/j.heliyon.2021.e06367

Table 2.

Anticholinesterase activities of the isolated compounds from Ziziphus oxyphylla.

Compound Concentrations (μg/mL) Percent AChE (mean ± SEM) AChE IC50 (μg/mL) Percent BChE (mean ± SEM) BChE IC50 (μg/mL)
V 1000 83.4 ± 0.5∗∗∗ 80 83.2 ± 1.1∗∗∗ 80
500 74.1 ± 0.9∗∗∗ 72.6 ± 1.3∗∗
250 65.9 ± 1.4∗∗∗ 64.9 ± 0.1∗∗∗
125 56.1. ± 1.4∗∗ 55.9 ± 1.0∗∗
62.5 48.2 ± 1.4∗∗∗ 48.1 ± 1.9∗
VI 1000 80.7 ± 1.1∗∗ 90 79.8 ± 1.4∗∗ 91
500 71.2 ± 1.8∗∗ 71.1 ± 1.6∗∗
250 62.1 ± 2.0∗∗ 61.4 ± 0.3∗∗∗
125 54.7. ± 1.6∗∗∗ 53.5 ± 1.6∗∗
62.5 47.2 ± 1.5∗∗∗ 47.0 ± 1.1∗∗
VII 1000 80.1 ± 1.2∗∗ 89 80.0 ± 1.1∗∗ 90
500 71.5 ± 1.6∗∗ 71.1 ± 0.8∗∗
250 62.3 ± 1.1∗∗ 62.1 ± 0.0∗∗∗
125 54.1. ± 1.2∗∗∗ 53.4 ± 1.1∗∗
62.5 47.8 ± 1.3∗∗∗ 47.2 ± 1.2∗∗
Galantamine 1000 92.1 ± 1.0 40 92.0 ± 0.8 43
500 82.3 ± 1.2 81.8 ± 1.4
250 73.4 ± 0.5 71.8 ± 1.5
125 64.2. ± 1.2 64 .0 ± 1.2
62.5 55.6 ± 2.6 54.1 ± 1.0

Data presented as mean ± SEM; Values differ significantly compared to the positive control, ns: P > 0.05∗: P < 0.05, ∗∗∗: P < 0.001, n = 3.