Table 2.
Occurrence of treatment discontinuation.
| Characteristic | N = 191 |
|---|---|
| OCA discontinuation, n | 33 (17%) |
| Time of OCA discontinuation | |
| Before 6 months | 17 (52%) |
| Between 6 and 12 months | 16 (48%) |
| Reason for OCA discontinuation | |
| Pruritus | 21 (64%) |
| Worsening liver function | 3 (9.1%) |
| Worsening liver enzymes | 1 (3%) |
| Anaemia | 2 (6.1%) |
| Death from TIPS complications | 1 (3.0%) |
| Demyelinating disease | 1 (3.0%) |
| Dizzying syndrome | 1 (3.0%) |
| Headache | 1 (3.0%) |
| Myalgia | 1 (3.0%) |
| OCA intolerance | 1 (3.0%) |
Data are expressed as number (percentage). OCA, obeticholic acid; TIPS, transjugular intrahepatic portosystemic shunt.