Table 3.
Properties and incidence of CS in each semicircular canal based on group.
| CS incidence per trial (%) | PICA (n = 17) | VN (n = 17) | HS (n = 17) | p-value (PICA vs. VN) | p-value (PICA vs. HS) | ||||
|---|---|---|---|---|---|---|---|---|---|
| i | c | i | c | i | c | i | c | ||
| HC | 63.3% | 70.6% | 92.6% | 23.2% | 18.2% | <0.001a | <0.001a | <0.001a | <0.001a |
| PC | 68.2% | 63.8% | 52.7% | 49.7% | 9.4% | <0.001a | <0.001a | <0.001a | <0.001a |
| AC | 27.7% | 21.6% | 61.1% | 23.9% | 5.8% | <0.001a | 0.54a | <0.001a | <0.001a |
| CS amplitude°, mean ± SD (95% CI) | |||||||||
| HC | 1.34 ± 0.94 (0.86–1.83) | 1.39 ± 0.92 (0.92–1.86) |
4.00 ± 1.36 (3.25–4.75) | 0.75 ± 0.82 (0.29–1.20) |
0.48 ± 0.29 (0.38–0.58) | <0.001b | 0.03b | <0.001b | <0.001b |
| PC | 1.84 ± 1.81 (0.91–2.77) | 1.78 ± 1.98 (0.76–2.80) |
1.10 ± 1.00 (0.55–1.66) | 0.96 ± 0.70 (0.57–1.35) |
0.27 ± 0.33 (0.15–0.38) | 0.22b | 0.37b | <0.001b | <0.001b |
| AC | 0.91 ± 0.96 (0.42–1.41) | 0.55 ± 0.58 (0.25–0.84) |
2.28 ± 1.16 (1.63–2.92) | 0.70 ± 0.85 (0.23–1.17) |
0.25 ± 0.32 (0.13 ± 0.36) | <0.001b | 0.74b | 0.003b | 0.082b |
| CSsd (95% CI) | |||||||||
| HC | 0.47 ± 0.61 (0.15–0.78) |
3.26 ± 1.47 (2.44–4.07) |
0.25 ± 0.32 (0.09–0.41) | <0.001b | 0.081b | ||||
| PC | 0.35 ± 0.40 (0.15–0.56) |
0.42 ± 0.47 (0.16–0.68) |
0.21 ± 0.25 (0.09–0.33) | 0.85b | 0.146b | ||||
| AC | 0.54 ± 0.67 (0.20–0.89) |
1.62 ± 0.85 (1.15–2.10) |
0.33 ± 0.36 (0.16–0.51) | 0.001b | 0.363b | ||||
| Latency of CS (msec) (95% CI) | |||||||||
| HC | 348.5 ± 54.1 (321.1–375.9) | 360.3 ± 62.2 (329.9–390.8) |
336.1 ± 43.4 (314.1–358.0) | 350.0 ± 87.9 (295.5–404.5) |
405.3 ± 62.4 (381.8–428.9) | 0.49b | 0.73b | 0.005b | 0.047b |
| PC | 374.8 ± 84.5 (333.4–416.2) | 368.4 ± 85.2 (326.7–410.2) |
338.4 ± 64.9 (299.9–363.9) | 326.7 ± 63.1 (289.4–363.9) |
431.7 ± 57.2 (404.6–458.9) | 0.24b | 0.18b | 0.029b | 0.019b |
| AC | 404.1 ± 95.3 (352.3–455.9) | 415.8 ± 73.2 (370.4–461.2) |
374.2 ± 75.7 (334.5–413.8) | 366.1 ± 84.9 (303.0–429.02) |
418.0 ± 40.1 (397.0–439.0) | 0.37b | 0.22b | 0.544b | 0.585b |
| No. of subjects with bilateral CS | |||||||||
| HC | 14 (82.4%) | 12 (70.6%) | 8 (47.1%) | 0.688c | 0.031 | ||||
| PC | 16 (94.1%) | 12 (70.6%) | 6 (35.3%) | 0.175c | <0.001c | ||||
| AC | 9 (52.9%) | 8 (47.1%) | 6 (35.3%) | 1.000c | 0.300c | ||||
PICA, posterior inferior cerebellar artery; VN, vestibular neuritis; HS, healthy subjects; HC, horizontal canal; PC, posterior canal; AC, anterior canal; CS, corrective saccade; SD, standard deviation; CI, confidence interval; i, ipsilesional; c, contralesional.
a
chi-square test;
b
Mann–Whitney U test;
c
Fisher's exact test;
d
CS asymmetry (CSs) was defined as the absolute difference between ipsilesional and contralesional CS amplitudes. The value in parentheses below the mean ± SD represents the 95% CI.