Table 3.
Traditional maximum grade AE analysis comparing the proportion of patients with and without grade ≥ 3 AE
| Adverse event, characteristic | Grade <3 AE, n (%) | Grade ≥3 AE, n (%) | p value |
|---|---|---|---|
| Fatigue | |||
| Age <65 | 250 (90.3) | 27 (9.7) | .01 |
| Age ≥65 | 206 (82.7) | 43 (17.3) | |
| PS 0–1 | 382 (87.2) | 56 (12.8) | .43 |
| PS 2 | 74 (84.1) | 14 (15.9) | |
| Neuropathy | |||
| Age <65 | 254 (91.4) | 24 (8.6) | .03 |
| Age ≥65 | 211 (85.4) | 36 (14.6) | |
| PS 0–1 | 386 (87.9) | 53 (12.1) | .29 |
| PS 2 | 79 (91.9) | 7 (8.1) |
Abbreviations: AE, adverse event; PS, performance status.