Drug 1 | |
Generic/Working Name | PHY906, KD018, YIV‐906 |
Trade Name | YIV‐906 |
Company Name | Yiviva Inc. |
Dose | 800 b.i.d. milligrams (mg) per day |
Route | Oral (p.o.) |
Schedule of Administration | Patients were initially treated for two 21‐day courses with PHY906 800 mg b.i.d. + capecitabine 750 mg/m2 b.i.d. according to the following schedule: capecitabine 14 days on treatment, days 1 through 14, and 7 days off treatment; PHY906 days 1 through 4 and days 8 through 11 of each course. Patients might remain on study beyond their initial two courses of treatment until tumor progression or unacceptable toxicity mandated their removal. |
Drug 2 | |
Generic/Working Name | Xeloda |
Trade Name | Capecitabine |
Company Name | Roche |
Dose | 750 milligrams (mg) per squared meter (m2) |
Route | Oral (p.o.) |
Schedule of Administration | Patients were initially be treated for two 21‐day courses with PHY906 800 mg b.i.d. + capecitabine 750 mg/m2 b.i.d. according to the following schedule: capecitabine 14 days on treatment and 7 days off treatment and PHY906 days 1 through 4 and days 8 through 11 of each course. Patients might remain on study beyond their initial two courses of treatment until tumor progression or unacceptable toxicity mandated their removal. |