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. 2021 Jan 11;26(3):e492–e499. doi: 10.1002/onco.13655

Table 4.

Odd ratios and 95% confidence intervals of factors associated with latent classes of health‐related quality of life

Covariates Class 2, OR (95% CI) Class 3, OR (95% CI) Class 4, OR (95% CI) Class 5, OR (95% CI)
Intercept (ref = class 1) 0.33 (0.06–1.66) 0.38 (0.05–2.73) 0.00 (0.00–0.02) a 0.05 (0.00–0.61) a
Sex (ref = male): Female 1.63 (1.14–2.32) a 2.01 (1.31–3.10) a 1.48 (0.82–2.69) 1.86 (1.13–3.07) a
Age, years 1.00 (0.98–1.02) 0.98 (0.96–1.01) 1.07 (1.02–1.14) a 1.00 (0.96–1.03)
Socioeconomic status (ref = low)
Medium 1.31 (0.80–2.13) 0.82 (0.48–1.39) 0.60 (0.29–1.26) 1.18 (0.62–2.25)
High 0.99 (0.60–1.64) 0.55 (0.31–0.98) a 0.95 (0.47–1.92) 0.96 (0.49–1.89)
No. comorbid conditions (ref = none)
One 1.76 (1.09–2.85) a 1.45 (0.73–2.87) 3.75 (0.82–17.16) 3.09 (1.07–8.89) a
More than one 4.34 (2.67–7.05) a 7.66 (4.20–13.98) a 17.66 (4.27–73.11) a 20.67 (7.72–55.38) a
Time since diagnosis, years 0.92 (0.87–0.98) a 1.00 (0.92–1.07) 0.94 (0.85–1.04) 0.84 (0.77–0.93) a
TNM stage (ref = stage I)
Stage II 1.08 (0.69–1.67) 1.20 (0.66–2.19) 0.98 (0.49–1.95) 0.82 (0.42–1.57)
Stage III 1.48 (0.76–2.91) 2.07 (0.84–5.13) 1.27 (0.44–3.64) 2.11 (0.86–5.19)
Differentiation grade (ref = moderately differentiated)
Poorly differentiated 0.92 (0.51–1.64) 0.77 (0.39–1.52) 1.67 (0.51–5.41) 1.04 (0.45–2.37)
Well differentiated 0.81 (0.39–1.69) 0.91 (0.40–2.09) 1.59 (0.37–6.78) 1.41 (0.52–3.80)
Topography (ref = distal): Proximal 1.23 (0.84–1.79) 1.26 (0.80–1.98) 0.98 (0.56–1.73) 1.68 (0.98–2.86)
Histology (ref = adenocarcinoma): Mucinous 1.20 (0.69–2.08) 0.84 (0.42–1.68) 1.41 (0.60–3.28) 1.87 (0.96–3.62)
Treatment (ref = surgery only): Surgery and adjuvant chemotherapy 0.82 (0.45–1.50) 0.76 (0.33–1.72) 0.56 (0.20–1.52) 0.55 (0.25–1.23)

Odds ratios reported in this table are based on a multinomial logistic regression and therefore adjusted for all other covariates in the model. Covariates with missing cases (see Table 1) were imputed using mean imputation.

a

Statistically significant effects.

Abbreviations: CI, confidence interval; OR, odds ratio.