Table 4.
Covariates | Class 2, OR (95% CI) | Class 3, OR (95% CI) | Class 4, OR (95% CI) | Class 5, OR (95% CI) |
---|---|---|---|---|
Intercept (ref = class 1) | 0.33 (0.06–1.66) | 0.38 (0.05–2.73) | 0.00 (0.00–0.02) a | 0.05 (0.00–0.61) a |
Sex (ref = male): Female | 1.63 (1.14–2.32) a | 2.01 (1.31–3.10) a | 1.48 (0.82–2.69) | 1.86 (1.13–3.07) a |
Age, years | 1.00 (0.98–1.02) | 0.98 (0.96–1.01) | 1.07 (1.02–1.14) a | 1.00 (0.96–1.03) |
Socioeconomic status (ref = low) | ||||
Medium | 1.31 (0.80–2.13) | 0.82 (0.48–1.39) | 0.60 (0.29–1.26) | 1.18 (0.62–2.25) |
High | 0.99 (0.60–1.64) | 0.55 (0.31–0.98) a | 0.95 (0.47–1.92) | 0.96 (0.49–1.89) |
No. comorbid conditions (ref = none) | ||||
One | 1.76 (1.09–2.85) a | 1.45 (0.73–2.87) | 3.75 (0.82–17.16) | 3.09 (1.07–8.89) a |
More than one | 4.34 (2.67–7.05) a | 7.66 (4.20–13.98) a | 17.66 (4.27–73.11) a | 20.67 (7.72–55.38) a |
Time since diagnosis, years | 0.92 (0.87–0.98) a | 1.00 (0.92–1.07) | 0.94 (0.85–1.04) | 0.84 (0.77–0.93) a |
TNM stage (ref = stage I) | ||||
Stage II | 1.08 (0.69–1.67) | 1.20 (0.66–2.19) | 0.98 (0.49–1.95) | 0.82 (0.42–1.57) |
Stage III | 1.48 (0.76–2.91) | 2.07 (0.84–5.13) | 1.27 (0.44–3.64) | 2.11 (0.86–5.19) |
Differentiation grade (ref = moderately differentiated) | ||||
Poorly differentiated | 0.92 (0.51–1.64) | 0.77 (0.39–1.52) | 1.67 (0.51–5.41) | 1.04 (0.45–2.37) |
Well differentiated | 0.81 (0.39–1.69) | 0.91 (0.40–2.09) | 1.59 (0.37–6.78) | 1.41 (0.52–3.80) |
Topography (ref = distal): Proximal | 1.23 (0.84–1.79) | 1.26 (0.80–1.98) | 0.98 (0.56–1.73) | 1.68 (0.98–2.86) |
Histology (ref = adenocarcinoma): Mucinous | 1.20 (0.69–2.08) | 0.84 (0.42–1.68) | 1.41 (0.60–3.28) | 1.87 (0.96–3.62) |
Treatment (ref = surgery only): Surgery and adjuvant chemotherapy | 0.82 (0.45–1.50) | 0.76 (0.33–1.72) | 0.56 (0.20–1.52) | 0.55 (0.25–1.23) |
Odds ratios reported in this table are based on a multinomial logistic regression and therefore adjusted for all other covariates in the model. Covariates with missing cases (see Table 1) were imputed using mean imputation.
Statistically significant effects.
Abbreviations: CI, confidence interval; OR, odds ratio.