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Serum 6-hydroxymelatonin sulfate levels from MEL-P in non-pregnant healthy control subjects (n = 30) compared to pregnant subjects throughout pregnancy (n = 26). **, significantly different from pregnant women in the first, second, and third trimesters (all P < 0.0001, Wilcoxon-Mann Whitney test). Data are shown as median, interquartile, and full range. NS, non significant.
