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. 2021 Feb 18;12:626390. doi: 10.3389/fendo.2021.626390

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Copyright © 2021 Feng, Wang, Sun, Dong, Yu, Huang and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROS formation in mouse renal tissues. (A, B). Representative photographs and quantification of ROS formation (red) in mouse kidneys by dihydroethidium staining (six sections per mouse were analyzed). (C). Representative photographs and quantification of gp91 phox in mouse kidneys measured by western blot. Male mice, n = 6/group. *P < 0.05, vs db/m group; ^# P < 0.05, vs db/db group. Db/m, db/m mice; db/db, db/db mice without Ferrostatin-1 treatment; db/db+Fer1, db/db mice with Ferrostatin-1 treatment. Data are means ± S.E.M.