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. 2021 Feb 18;12:626390. doi: 10.3389/fendo.2021.626390

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Copyright © 2021 Feng, Wang, Sun, Dong, Yu, Huang and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lipid peroxidation and GPX4 in mouse renal tissues. (A–D). Quantification of malondialdehyde (MDA) (A), superoxide dismutase (SOD) (B), catalase (CAT) (C) and glutathione peroxidases (GSH-Px) (D) in mouse kidneys. (E). Representative photographs and quantification of glutathione peroxidase 4 (GPX4) in mouse kidneys measured by western blot. Male mice, n = 6–9/group. *P < 0.05, vs db/m group; ^# P < 0.05, vs db/db group. Db/m, db/m mice; db/db, db/db mice without Ferrostatin-1 treatment; db/db+Fer1, db/db mice with Ferrostatin-1 treatment. Data are means ± S.E.M.