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. 2021 Feb 23;8:415–421. doi: 10.1016/j.toxrep.2021.02.019

Table 1.

Mean number of erythrocytic nuclear abnormalities (ENA) in zebrafish exposed to three sub-lethal concentrations (0.8, 1.6 and, 3.2 mg/L, i.e., 10 %, 20 %, and 40 % of LC50, respectively) of fenitrothion and the respective controls at each period of exposure (1, 3 and 7 days) and recovery for similar intervals.

Abnormalities Dose (% of LC50) Exposure period
Recovery period Recovery rate (%) Exposure period Recovery period Recovery rate (%) Exposure period Recovery period Recovery rate (%)
Control 1 day 1 day 3 day 3 day 7 day 7 day
Micronuclei 10 0.33 ± 0.10 ax 0.48 ± 0.02a 0.40 ± 0.01x 16.66 1.50 ± 0.11b 1.12 ± 0.30y 25.33 4.18 ± 0.22c 1.68 ± 0.13z 59.80
20 0.68 ± 0.03 a 0.60 ± 0.01 x 11.76 1.71 ± 0.13 b 1.40 ± 0.18 y 18.12 4.84 ± 0.13 c 2.12 ± 0.05z 56.19
40 0.87 ± 0.12 a 0.74 ± 0.11 x 14.94 1.80 ± 0.20 b 1.50 ± 0.17 y 16.66 5.79 ± 0.21 c 3.21 ± 0.20 z 44.55
Binucleated 10 0.29 ± 0.03 ax 0.51 ± 0.14ab 0.45 ± 0.11 x 11.76 0.33 ± 0.13 a 0.25 ± 0.09y 24..24 0.84 ± 0.02 b 0.55 ± 0.11 x 34.52
20 0.73 ± 0.05 a 0.64 ± 0.19 x 12.32 0.69 ± 0.21 a 0.57 ± 0.15 x 17.39 1.15 ± 0.13 b 0.78 ± 0.09 x 32.17
40 0.48 ± 0.14 a 0.44 ± 0.05 x 8.33 0.62 ± 0.16 b 0.50 ± 0.21 x 19.35 1.18 ± 0.14 c 0.82 ± 0.05 y 30.50
Blebbed nuclei 10 0.35 ± 0.11 ax 0.77 ± 0.05 a 0.65 ± 0.14 x 15.58 1.20 ± 0.05 b 0.86 ± 0.07 y 28.33 1.95 ± 0.12 c 1.12 ± 0.09 z 42.56
20 0.96 ± 0.16 a 0.84 ± 0.13 x 12.50 1.57 ± 0.05 b 1.00 ± 0.06 y 26.75 2.10 ± 0.23 c 1.30 ± 0.11 y 38.09
40 1.13 ± 0.04 b 1.00 ± 0.11 x 11.50 1.55 ± 0.06 b 1.25 ± 0.10 x 19.35 2.55 ± 0.25 c 1.60 ± 0.20 y 37.25
Notched nuclei 10 0.15 ± 0.05 ax 0.29 ± 0.04 a 0.25 ± 0.08 x 13.79 0.93 ± 0.12 b 0.78 ± 0.20 y 16.12 1.76 ± 0.3 c 0.89 ± 0.18 y 49.43
20 0.56 ± 0.06 a 0.49 ± 0.09 x 12.50 1.03 ± 0.12 b 0.85 ± 0.13 y 17.47 2.69 ± 0.42 c 1.59 ± 0.10 z 40.08
40 0.70 ± 0.03 a 0.62 ± 0.16 x 11.42 1.40 ± 0.12 b 1.18 ± 0.36 y 15.71 3.96 ± 1.09 c 2.60 ± 0.10 z 34.34
Nuclear bridge 10 0.18 ± 0.02 ax 0.27 ± 0.08 a 0.22 ± 0.08 x 18.51 1.57 ± 0.08 b 0.98 ± 0.27 y 37.57 1.90 ± 0.07 c 0.90 ± 0.02 y 52.63
20 0.25 ± 0.02 a 0.21 ± 0.08 x 16.00 1.25 ± 0.12 b 1.00 ± 0.08 y 20.00 2.46 ± 0.27 c 1.50 ± 0.17 z 39.02
40 0.37 ± 0.11 a 0.33 ± 0.06 x 10.81 1.40 ± 0.14 b 1.06 ± 0.11 y 24.28 3.33 ± 0.19 c 2.21 ± 0.15 z 33.63
Nuclear bud 10 0.10 ± 0. ± 01ax 0.13 ± 0.07 a 0.11 ± 0.06 x 15.38 0.40 ± 0.04ab 0.29 ± 0.06 x 27.50 0.75 ± 0.04 b 0.44 ± 0.05 y 41.33
20 0.20 ± 0.05 a 0.18 ± 0.06 x 10.00 0.50 ± 0.09ab 0.37 ± 0.14 x 26.00 0.94 ± 0.05 b 0.68 ± 0.08 y 27.65
40 0.30 ± 0.11 a 0.26 ± 0.01 x 13.33 0.68 ± 0.25 b 0.52 ± 0.13x 23.52 1.00 ± 0.04 c 0.74 ± 0.05 y 26.00

Values with different alphabet superscripts in the same row differ significantly (p < 0.05) between exposure and recovery periods, respectively in ENA cells. All values are expressed as mean±SD.