TABLE 6.

Physicochemical properties and drug loading of andrographolide nanoformulation with different PVA concentration.

Formulation code	Particle size (nm)	Polydispersity index–PI	Zeta potential (mV)	Drug loading (%)	Encapsulation efficiency (%)
E1	1631***	0.170.02	−14.11.1	2.50.2	24.31.7
E2	1144***	0.170.04	−11.61.3	2.80.4*	27.33.6
E3	1332	0.200.03	−10.12.0	2.20.3	23.23.7
E4	1371	0.200.03	−12.60.3	1.20.1**	12.60.5**
E5	1291	0.160.07	−13.53.5	1.30.1**	13.40.9**

Results are expressed as mean ± S.D (n = 3). *signifies p < 0.05, **signifies p < 0.01, ***signifies p < 0.001 significant differences with respect to E3 formulation. E1, PVA 1% w/v, E2, PVA 2% w/v, E3, PVA 2.5% w/v, E4, PVA 3% w/v, E5, PVA 4% w/v.