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Physicochemical properties and drug loading of optimized andrographolide nanoformulation.
| Formulation code | Particle size (nm) | Polydispersity index–PI | Zeta potential (mV) | Drug loading (%) | Encapsulation efficiency (%) |
| Ethyl acetate | 1354*** | 0.220.00*** | −11.72.4 | 2.60.6* | 19.14.1*** |
| Chloroform | 1942 | 0.100.01 | −17.25.6 | 1.30.2 | 9.71.7 |
Results are expressed as mean ± SD (n = 3). *signifies p < 0.05, ***signifies p < 0.001 significant differences with respect to 85:15 chloroform formulation.
