Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Evaluation of the matrix effect of metabolites of 5-FU from cellular content, DNA and RNA extracts.
| Matrix | Metabolites | Matrix effect (%) |
|---|---|---|
| Cellular content | 5-FUrd | +20 |
| 5-FUMP | −24 | |
| 5-FUTP | +20 | |
| 5-FdUrd | +20 | |
| 5-FdUMP | +50 | |
| 5-FdUTP | −39 | |
| RNA extract | 5-FUrd | <10 |
| 5-FUMP | −56 | |
| DNA extract | 5-FdUrd | <10 |
| 5-FdUMP | −35 |
