Table 2. Clinical features of trilateral/quadrilateral retinoblastoma.
| Feature | Outcome |
|---|---|
| Patients (n) | 14 |
| Incidence in RB | 1% |
| Incidence in bilateral RB | 3.5% |
| TRB (n) | 12 |
| QRB (n) | 2 |
| Age at Dx of intraocular RB (months) | 12.7±8.8 |
| Age at Dx of TRB/QRB (months) | 16.6±14.8 |
| Months from Dx to TRB/QRB (months) | 18.3±8.0 |
| Age of concurrent TRB/QRB (months) | 11.1±7.4 |
| Age of later onset TRB (months) | 37±19.1 |
| 1-year OS rate | 80.00% |
| 2-year OS rate | 18.75% |
| 3-year OS rate | 12.50% |
RB, retinoblastoma; TRB, trilateral retinoblastoma; QRB, quadrilateral retinoblastoma; Dx, diagnosis; OS, overall survival.