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. 2021 Apr;11(4):1368–1380. doi: 10.21037/qims-20-538

Table 4. Comparison of the diagnostic performance of the BETNET model with three machine-learning algorithms in the validation dataset.

Parameters BETNET SE_Net SE_inception_v4 Xception
AUC, 95% CI 0.983 (0.973–0.990) 0.963 (0.949–0.974) 0.971 (0.959–0.980) 0.964 (0.951–0.975)
Sensitivity (%) 99.19 94.20 96.20 97.80
Specificity (%) 97.45 98.40 98.00 95.00
Accuracy (%) 98.3 96.3 97.1 96.4
Youden index 0.9663 0.9276 0.9420 0.9287
P 0.0004* 0.0337* 0.0027*

AUCs of the BETNET model and the other three models were calculated by DeLong et al.’s. method. P: The difference of AUCs between the BETNET model and other three models was compared by Z-test; *, P<0.05. AUC, area under the ROC curve; CI, confidence interval.