Table 5. Diagnostic capability of STE in identifying significant fibrosis, severe fibrosis and cirrhosis.
Distinction | P value | AUC (95% CI) | Cutoff values | Accuracy (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
---|---|---|---|---|---|---|---|---|
≥ Stage 2 (n=67 vs. n=35) | <0.001 | 0.82 (0.73–0.89) | 9.07 kPa (1.74 m/s) | 80.4 | 79.1 | 80.0 | 88.3 | 66.7 |
≥ Stage 3 (n=30 vs. n=72) | <0.001 | 0.87 (0.78–0.93) | 9.97 kPa (1.82 m/s) | 77.5 | 93.3 | 70.8 | 57.1 | 96.2 |
Stage 4 (n=17 vs. n=85) | <0.001 | 0.91 (0.83–0.96) | 10.48 kPa (1.87 m/s) | 76.5 | 100 | 71.8 | 41.5 | 100 |
STE, sound touch elastography; AUC, area under the receiver operating characteristic curve; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.