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. 2021 Feb 18;9:607121. doi: 10.3389/fcell.2021.607121

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Copyright © 2021 Schneider, De Cegli, Nagarajan, Kretschmer, Matthiessen, Intartaglia, Hotaling, Ueffing, Boldt, Conte and May-Simera.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic analysis shows an increase in mis-regulated proteins in P29 Bbs8^−/− RPE. (A) Volcano plot showing significantly up-regulated (red) and down-regulated (green) proteins in P11 Bbs8^−/− RPE compared to controls. (B) Volcano plot showing significantly up-regulated (red) and down-regulated (green) proteins in P11 Bbs8^−/− RPE compared to controls. (C) Comparison of Proteome and Transcriptome data. Chart shows commonly up or down-regulated molecules at P29 with gene symbols, descriptions and related GO terms.