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. 2021 Feb 18;12:625610. doi: 10.3389/fphar.2021.625610

TABLE 3.

Cox regression model for predictors of hospitalization and death in a cohort of 175 patients admitted for treatment of CUD in metropolitan Barcelona, Spain.

Hospitalitzation Death
Unadjusted HR (95% CI) Multivariate HR (95% CI) Unadjusted HR (95% CI) Multivariate HR (95% CI)
Women 1.89 (1.21–2.96) 1.61 (1.01–2.58) 1.07 (0.43–2.65)
Age at starting cocaine use: 5 years increase 1.15 (0.93–1.43) 0.93 (0.57–1.52)
Non-intranasal cocaine 0.94 (0.62–1.41) 2.30 (1.05–5.03) 1.64 (0.69–3.92)
Duration of CUD 0.99 (0.99–1.00) 1.00 (0.99–1.01)
AUD 1.23 (1.05–1.44) 1.27 (1.08–1.48) 0.96 (0.67–1.38)
Urine screening at admission
 Opiates 0.72 (0.35–1.50) 1.28 (0.38–4.32)
 Cannabis 0.84 (0.55–1.29) 1.49 (0.67–3.32)
VACS index
 <20 1 1 1 1
 20–39 1.30 (0.81–2.08) 1.24 (0.77–2.02) 2.39 (1.02–5.59) 1.86 (0.73–4.72)
 >40 2.63 (1.25–5.52) 2.64 (1.20–5.83) 4.35 (1.55–12.2) 3.52 (1.19–10.4)

Statistically significant differences are in bold. AUD, alcohol use disorder; CUD, cocaine use disorder; CI, confidence interval; HR: hazard ratio.