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Morphogenic signaling mediated by the 5-HT7R. AC, Adenylyl cyclase; cAMP, cyclic adenosine monophosphate; Cdc42, cell division cycle protein 42; Cdk5, cyclin-dependent kinase 5; EPAC, exchange protein directly activated by cAMP; Erk, extracellular-regulated kinase; mTOR, mammalian target of rapamycin; PKA, protein kinase A; RhoA, Ras homolog gene family member A; CD44, hyaluronic acid receptor; MMP9, metallo proteinase 9; ECM, extracellular matrix.
